Side Effects of Domperidone

When dealing with Domperidone, a dopamine‑blocking drug used to boost gut movement and reduce nausea. It’s also known as Motilium, and belongs to the class of prokinetic agents, medicines that speed up gastrointestinal motility. Because it blocks dopamine receptors outside the brain, Domperidone can trigger a range of unwanted reactions.

One of the most talked‑about reactions is QT prolongation, a lengthening of the heart’s electrical cycle that can lead to arrhythmias. This cardiac effect is why doctors often check an ECG before prescribing high doses. Another frequent complaint is extrapyramidal symptoms such as tremor or stiffness, which mirror the side effects seen with Metoclopramide, another dopamine antagonist used for similar digestive issues. In short, side effects of Domperidone encompass heart rhythm changes, movement disorders, and occasional hormonal disturbances like increased prolactin.

What to watch out for

Understanding how these entities connect helps you stay safe. Domperidone is a prokinetic agent that improves gastric emptying, but it requires monitoring of cardiac health because of its QT‑prolonging potential. Prokinetic agents depend on dopamine blockade, which also explains why Metoclopramide shares similar neurological side effects. If you notice palpitations, dizziness, or unexplained muscle jerks, it’s a sign to talk to your pharmacist or doctor right away. The collection below breaks down each adverse effect, offers tips on risk reduction, and compares Domperidone with other gut‑motility drugs so you can make an informed decision.