Tag: proton pump inhibitors

Levothyroxine and Proton Pump Inhibitors: What You Need to Know About Absorption Interactions

• by Colin Edward Egan
• on 9 Dec 2025

Levothyroxine and proton pump inhibitors (PPIs) can interact, reducing thyroid hormone absorption. Nearly 2.7 million Americans on both drugs may need dose adjustments or alternatives like liquid levothyroxine or H2 blockers.