Artichoke Supplements: May 2024 — Benefits, Uses, and How to Choose
Artichoke leaf extract can help digestion, support the liver, and improve cholesterol. Clinical trials found reductions in LDL cholesterol of about 10–20% over 6–12 weeks when people used standardized artichoke leaf extract. That makes it worth considering if you want a natural boost alongside diet and exercise.
What does artichoke do for digestion and liver?
Artichoke contains compounds like cynarin and flavonoids that stimulate bile flow and aid fat digestion. Many people report less bloating and faster digestion after a few weeks. For liver support, antioxidants in artichoke help reduce oxidative stress in liver cells in lab studies and small human trials.
Who should try artichoke supplements? If you have mild digestive discomfort, occasional bloating after meals, or mildly elevated LDL cholesterol, artichoke extract may help. It is not a replacement for prescribed medicine for serious liver disease or high cholesterol. Talk with your doctor if you take statins or other prescription drugs.
How to choose and use a supplement
Look for supplements standardized for cynarin or total polyphenols and follow the maker's dosage. Common doses in studies range from 300 to 640 mg of extract per day, divided with meals. Start with the lower dose to check tolerance. Capsules and tablets are most common, but tinctures and teas are options too.
Safety and side effects: Side effects are usually mild: gas, upset stomach, or allergic reactions if you're sensitive to plants in the Asteraceae family (like ragweed). Avoid artichoke supplements if you have an obstructed bile duct or gallstones without medical advice. Pregnant and breastfeeding people should skip them unless a clinician approves.
Practical tips I use and recommend: Take artichoke extract with meals that contain some fat - it helps absorption. Pair the supplement with a fiber-rich diet and exercise to get the most benefit for cholesterol. Keep a short symptom diary for two to four weeks to see if digestion improves.
How long should you try artichoke extract? Most studies measured effects at 6 to 12 weeks, so plan a trial of at least six weeks. Watch for lower bloating, fewer reflux episodes, or modest cholesterol changes on follow-up blood tests. If you see no benefit after three months, stop and reassess. If side effects start, stop immediately and talk with your clinician.
Product safety and labels: choose third-party testing, avoid high fillers, check for heavy metals, store in a cool dry place. For people on blood thinners? Artichoke hasn't shown strong blood-thinning effects but check with your doctor. Want product picks? See our May post for a shortlist and links to studies.
Healthy habits matter: supplements add to good food and movement, not replace them. Find full details and product picks in May.

Health Benefits of Artichoke Dietary Supplements: Enhancing Your Well-being
- by Colin Edward Egan
- on 10 May 2024